CBFA2T3 Antibody, HRP conjugated
Product Sizes
50 ug
£186.00
CSB-PA004576LB01HU-50UG
100 ug
£334.00
CSB-PA004576LB01HU-100UG
About this Product
- SKU:
- CSB-PA004576LB01HU
- Additional Names:
- Cbfa2t3 antibody; Ccore binding factor runt domain alpha subunit 2 translocated to 3 antibody; ETO2 antibody; hMTG16 antibody; hMTG16a antibody; hMTG16b antibody; MTG16 antibody; MTG16_HUMAN antibody; MTG8 related gene 2 antibody; MTG8 related protein MTG16a antibody; MTG8 related protein MTG16b antibody; MTG8-related protein 2 antibody; MTGR2 antibody; Myeloid translocation gene 8 and 16b antibody; Myeloid translocation gene on chromosome 16 protein antibody; Protein CBFA2T3 antibody; Zinc finger MYND domain-containing protein 4 antibody; ZMYND4 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Extra Details:
- Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Reduces the protein levels and stability of the transcriptinal regulator HIF1A; interacts with EGLN1 and promotes the HIF1A prolyl hydroxylation-dependent ubiquitination and proteasomal degradation pathway (PubMed:25974097). Contributes to inhibition of glycolysis and stimulation of mitochondrial respiration by down-regulating the expression of glycolytic genes including PFKFB3, PFKFB4, PDK1, PFKP, LDHA and HK1 which are direct targets of HIF1A (PubMed:23840896, PubMed:25974097). Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes (By similarity). Plays a role in granulocyte differentiation (PubMed:15231665).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Protein CBFA2T3 protein (39-159AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:CBFA2T3-Antibody-HRP-conjugated-12919289.html
