BVES Antibody
Product Sizes
50 ul
£186.00
CSB-PA002887ESR1HU-50UL
100 ul
£334.00
CSB-PA002887ESR1HU-100UL
About this Product
- SKU:
- CSB-PA002887ESR1HU
- Additional Names:
- Blood vessel epicardial substance antibody; Bves antibody; hBVES antibody; MGC42413 antibody; POP 1 antibody; POP1 antibody; POPD1_HUMAN antibody; POPDC 1 antibody; POPDC1 antibody; Popeye domain containing 1 antibody; Popeye domain containing protein 1 antibody; Popeye domain-containing protein 1 antibody; Popeye protein 1 antibody
- Application:
- ELISA, Immunofluorescence
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Blood vessel epicardial substance protein (241-360AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:BVES-Antibody-11909362.html
