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Antibodies

Birc5 Antibody

Product Sizes
50 ug
£186.00
CSB-PA002706HA01MO-50UG
100 ug
£334.00
CSB-PA002706HA01MO-100UG
About this Product
SKU:
CSB-PA002706HA01MO
Additional Names:
Birc5 antibody; Api4 antibody; Iap4Baculoviral IAP repeat-containing protein 5 antibody; Apoptosis inhibitor 4 antibody; Apoptosis inhibitor survivin antibody; TIAP antibody
Application:
ELISA, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Extra Details:
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7.
Host:
Rabbit
Immunogen:
Recombinant Mouse Baculoviral IAP repeat-containing protein 5 protein (1-140AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody