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Antibodies

ASAH2 Antibody

Product Sizes
50 ug
£186.00
CSB-PA002170EA01HU-50UG
100 ug
£334.00
CSB-PA002170EA01HU-100UG
About this Product
SKU:
CSB-PA002170EA01HU
Additional Names:
Acylsphingosine deacylase 2 antibody; AI585898 antibody; ASAH2 antibody; ASAH2_HUMAN antibody; BCDase antibody; hCD antibody; HNAC1 antibody; LCDase antibody; MGC129777 antibody; mitochondrial ceramidase antibody; N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2 antibody; N acylsphingosine amidohydrolase 2 antibody; N CDase antibody; N-acylsphingosine amidohydrolase 2 antibody; N-CDase antibody; NCDase antibody; Neutral ceramidase soluble form antibody; Non lysosomal ceramidase antibody; Non-lysosomal ceramidase antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Extra Details:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
Host:
Rabbit
Immunogen:
Recombinant Human Neutral ceramidase protein (255-506AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody