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Antibodies

ARIH2 Antibody

Product Sizes
50 ug
£186.00
CSB-PA002069LA01HU-50UG
100 ug
£334.00
CSB-PA002069LA01HU-100UG
About this Product
SKU:
CSB-PA002069LA01HU
Additional Names:
HT005 antibody; all trans retinoic acid inducible RING finger antibody; Ari 2 antibody; Ari-2 antibody; ARI2 antibody; ARI2_HUMAN antibody; Ariadne 2 antibody; Ariadne 2 protein homolog antibody; ariadne homolog 2 (Drosophila) antibody; ariadne homolog 2 antibody; Ariadne RBR E3 ubiquitin protein ligase 2 antibody; ARIH 2 antibody; Arih2 antibody; E3 ubiquitin protein ligase ARIH2 antibody; E3 ubiquitin-protein ligase ARIH2 antibody; protein ariadne 2 homolog antibody; Protein ariadne-2 homolog antibody; Triad 1 antibody; TRIAD1 antibody; Triad1 protein antibody; UIP48 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Extra Details:
E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:16118314, PubMed:17646546, PubMed:19340006, PubMed:24076655). Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity). The initial ubiquitin is then elongated (By similarity). E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed:24076655). Mediates 'Lys-6', 'Lys-48'-and 'Lys-63'-linked polyubiquitination (PubMed:16118314, PubMed:17646546, PubMed:19340006). May play a role in myelopoiesis (PubMed:19340006).
Host:
Rabbit
Immunogen:
Recombinant Human E3 ubiquitin-protein ligase ARIH2 protein (43-360AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody