RPA1 Monoclonal Antibody
Product Sizes
100 ul
£429.00
CSB-MA593248-100UL
About this Product
- SKU:
- CSB-MA593248
- Additional Names:
- Dmrpa1; Drosophila Replication Protein A; DRPA; HSSB; Human single stranded DNA binding protein; MST075; MSTP075; p70; REPA1; Replication factor A; Replication factor A protein 1; Replication protein A 70 kDa DNA-binding subunit
- Application:
- ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
- Buffer:
- Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
- Clonality:
- Monoclonal
- Extra Details:
- Plays an essential role in several cellular processes in DNA metabolism including replication,recombination and DNA repair.Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair;it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
- Host:
- Mouse
- Immunogen:
- Purified recombinant human RPA70 protein fragments expressed in E.coli.
- Isotype:
- IgG2a
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Non-human Primate, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:RPA1-Monoclonal-Antibody-11080346.html
