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Antibodies

ENG Monoclonal Antibody

Product Sizes
50 ul
£186.00
CSB-MA294403-50UL
100 ul
£334.00
CSB-MA294403-100UL
About this Product
SKU:
CSB-MA294403
Additional Names:
Endoglin (CD antigen CD105), ENG, END
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Monoclonal
Extra Details:
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
Host:
Mouse
Immunogen:
Synthesized peptide derived from human CD105(Endoglin)
Isotype:
IgG2b, kappa
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Monoclonal Antibody
IHC image of CSB-MA294403 diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-mouse IgG polymer labeled by HRP and visualized using 0.05% DAB.