GRB2 Monoclonal Antibody
Product Sizes
100 ul
£429.00
CSB-MA148138-100UL
About this Product
- SKU:
- CSB-MA148138
- Additional Names:
- Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb2; GRB2_HUMAN; Grb3 3
- Application:
- ELISA, Western Blot
- Clonality:
- Monoclonal
- Extra Details:
- Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
- Host:
- Mouse
- Immunogen:
- Purified recombinant human GRB2 protein fragments expressed in E.coli.
- Isotype:
- IgG1
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Non-human Primate, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:GRB2-Monoclonal-Antibody-11080057.html
