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Antibodies

MSH6 Monoclonal Antibody

Product Sizes
50 ug
£235.00
CSB-MA0150321A0M-50UG
100 ug
£392.00
CSB-MA0150321A0M-100UG
About this Product
SKU:
CSB-MA0150321A0M
Additional Names:
MutS Homolog 6,GTBP,HSAP2,DNA Mismatch Repair Protein Msh6,G/T Mismatch-Binding Protein
Application:
ELISA, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
translate.label.attr.clone:
2C12F3
Clonality:
Monoclonal
Extra Details:
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have beendescribed.
Host:
Mouse
Immunogen:
Recombinant Human MSH6 Protein
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Monoclonal Antibody