Alpha-Synuclein, Recombinant, Human
Product Sizes
0.1 mg
CSR-SYN04-2-0.1MG
About this Product
- SKU:
- CSR-SYN04-2
- Extra Details:
- E. coli expressed human A Alpha-synuclein has been widely used in structural and functional studies. Masuda et. al. (1) have reported that approximately 20% of E. coli expressed human A Alpha-syn is mistranslated resulting in a Cys residue instead of Tyr at position 136 and causing an increase in the levels of dimeric A Alpha-synuclein. CSR-SYN04 is E. coli human alpha-Synuclein (human) expressed from a plasmid in which the TAC codon coding for Tyr136 in the human protein is replaced by TAT to produce protein expressing Tyr at position 136 homogenously. It can be used as human A Alpha-syn under similar conditions to that of in vivo. This product can also be used for comparison (control) of A Alpha-Synuclein Fibrils (CSR-SYN03). Source: Human Expression System: E.coli Concentration: 1mg/mL Purity: ≥ 90% (SDS-Page) Storage: -20°C (1) Masuda M, Dohmae N, Nonaka T, Oikawa T, Hisanaga S, Goedert M, Hasegawa M. Cysteine misincorporation in bacterially expressed human alpha-synuclein. FEBS Lett. 2006 Mar 20;580(7):1775-9. doi: 10.1016/j.febslet.2006.02.032. Epub 2006 Feb 24. PMID: 16513114. Related Products, CSR
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins