Anti CLEC-2 monoclonal antibody (Clone 2A2B10)
Product Sizes
100 ul
£595.00
CAC-YAM-MA01-100UL
About this Product
- SKU:
- CAC-YAM-MA01
- Application:
- Flow Cytometry, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- 2A2B10|Clone 2A2B10
- Clonality:
- Monoclonal
- Extra Details:
- C-type lectin-like receptor 2 (CLEC-2) has been identified as a receptor for the platelet-activating snake venom rhodocytin. An endogenous ligand of CLEC-2 is the membrane protein podoplanin (PDPN), which is expressed on the surface of certain types of tumor cells and lymphatic endothelial cells (LECs). Deletion of CLEC-2 from platelets in mice results in death just after birth due to lung malformation and blood/lymphatic vessel separation. CLEC-2 protein is highly expressed in platelets and megakaryocytes and at lower levels in liver Kupffer cells and liver sinusoidal endothelial cells in humans. In mice, CLEC-2 is also expressed in neutrophils, dendritic cells, and macrophages at low levels., CAC
- Host:
- Rat
- Immunogen:
- CLEC-2
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Monoclonal Antibody
