Anti phospho TDP-43 (pS409/410) polyclonal antibody [replaces CAC-TIP-PTD-P01]
Product Sizes
100 ul
CAC-TIP-PTD-P07-100UL
About this Product
- SKU:
- CAC-TIP-PTD-P07
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- TDP-43, a heterogeneous nuclear ribonucleoprotein, was identified as a component of ubiquitin-positive and tau-negative inclusions observed in cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). Immunochemical analyses using antibodies generated against phospho- and non-phosphopeptides of human TDP-43 revealed that abnormally phosphorylated full-length TDP-43 (45 kDa), C-terminal fragments (~25 kDa) and smearing substances are deposited as intracellular inclusions in affected regions of FTLD-U and ALS cases. These antibodies are powerful tools for biochemical and immunohistochemical analyses of neurodegenerative diseases and for evaluation of cellular or animal models of TDP-43 proteinopathy., CAC
- Host:
- Rabbit
- Immunogen:
- phospho TDP-43 (pS409/410)
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Size:
- 100 ul
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Polyclonal Antibody
- PTM:
- Phosphorylated