Anti Interleukin-13 Receptor Subunit Alpha-1 (IL-13Ra) D1 Domain monoclonal antibody (Clone SS4B)
Product Sizes
100 ul
£595.00
CAC-SU-IZ-M03-100UL
About this Product
- SKU:
- CAC-SU-IZ-M03
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- Clone ss4b
- Clonality:
- Monoclonal
- Extra Details:
- The interleukin-13 receptor is a type I cytokine receptor, binding Interleukin-13. It consists of two subunits, encoded by IL13RA1 and IL4R, respectively. These two genes encode the proteins IL-13RA Alpha1 and IL-4RA Alpha. These form a dimer with IL-13 binding to the IL-13RA Alpha1 chain and IL-4RA Alpha stabilises this interaction. This IL-13 receptor can also instigate IL-4 signalling. In both cases this occurs via activation of the Janus kinase (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway, resulting in phosphorylation of STAT6. Phosphorylated STAT6 dimerises and acts as a transcription factor activating many genes, such as eotaxin., CAC
- Host:
- Rat
- Immunogen:
- Interleukin-13 Receptor Subunit Alpha-1 (IL-13Ra) D1 Domain
- Reactivities:
- Human
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Monoclonal Antibody
