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Antibodies

Anti Probable ATP-Dependent RNA Helicase DDX58 (RIG-I/RLR-1) monoclonal antibody (Clone SS1A)

Product Sizes
100 ul
£595.00
CAC-SU-IZ-M02-100UL
About this Product
SKU:
CAC-SU-IZ-M02
Application:
Western Blot
translate.label.attr.clone:
Clone ss1a
Clonality:
Monoclonal
Extra Details:
RIG-I like receptors (RLRs) are a family of DExD/H box RNA helicases that function as cytoplasmic sensors of pathogen-associated molecular patterns (PAMPs) within viral RNA (reviewed in (Onoguchi, Yoneyama et al. 2011)). The RLRs signal downstream transcription factor activation to drive type 1 interferon (IFN) production and antiviral gene expression that elicits an intracellular immune response to control virus infection. To date, three RLR members have been identified: RIG-I (retinoic acid-inducible gene I) - the founding member and therefore best characterized of this family, MDA5 (melanoma differentiation associated factor 5), and LGP2 (laboratory of genetics and physiology 2 and a homolog of mouse D11lgp2). Anti-RIG-I antibody is a rat monoclonal antibody obtained from immunization with a 16 amino acid peptide from the C-terminus of mouse RIG-I. This antibody can be used for the detection of mouse RIG-I by immunoblotting., CAC
Host:
Rat
Immunogen:
Probable ATP-Dependent RNA Helicase DDX58 (RIG-I/RLR-1)
Reactivities:
Mouse
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Supplier:
Cosmo Bio Ltd
Type:
Antibody: Monoclonal Antibody