Anti Achaete-Scute Homolog 2 (ASH-2/MASH-2) polyclonal antibody (Rabbit, Antiserum)
Product Sizes
100 ul
£479.00
CAC-SK-T01-004-100UL
About this Product
- SKU:
- CAC-SK-T01-004
- Application:
- Immunohistochemistry, Immunoprecipitation, Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- Component of the Set-2/Ash-2 histone methyltransferase (HMT) complex. Required for di- and trimethylation at Lys-4 of histone H3, a mark associated with epigenetic transcriptional activation. Implicated in the epigenetic inheritance of lifespan over several generations. Functions as a transcriptional regulator. Acts in the germline to limit soma longevity, probably by regulating a lipid metabolism pathway that signals from the germline to the intestine, thereby preventing accumulation of mono-unsaturated fatty acids. References: Koide et al. The expression of proprotein convertase PACE4 is highly regulated by Hash-2 in placenta: Possible role for placenta-specific basic helix-loop-helix transcription factor, human achaete-scute homologue-2. J. Biochem. 134. 433-440., CAC
- Host:
- Rabbit
- Immunogen:
- Achaete-Scute Homolog 2 (ASH-2/MASH-2)
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Polyclonal Antibody
