Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) polyclonal antibody (Rabbit, Antiserum)
Product Sizes
100 ul
£479.00
CAC-SK-T01-003-100UL
About this Product
- SKU:
- CAC-SK-T01-003
- Application:
- Immunohistochemistry, Immunoprecipitation, Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- Component of the RPD3C(L) histone deacetylase complex (HDAC). Responsible for the deacetylation of lysine residues on the N-terminal tails of core histones (H2A, H2B, H3 and H4). Histone deacetylation is a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. ASH1 is necessary to repress HO in daughter cells to block mating-type switching through its binding to HO promoter 5'-YTGAT-3' sites. It is also involved in pseudohyphal growth. References: Yoshida et al. (2001) Proprotein convertase PACE4 is down-regulated by the basic helix-loop-hekix transcription factor hash-1 and MASH-1. Biochem. J. 360, 683-689., CAC
- Host:
- Rabbit
- Immunogen:
- Achaete-Scute Homolog 1 (ASH-1/MASH-1)
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Polyclonal Antibody
