Anti Laminin Alpha-4 monoclonal antibody (Clone 652C4)
Product Sizes
2 ml
CAC-PRPG-LA4-M01-2ML
About this Product
- SKU:
- CAC-PRPG-LA4-M01
- Application:
- IHC-Frozen, IHC-Paraffin, Immunoprecipitation
- translate.label.attr.clone:
- Clone 652c4
- Clonality:
- Monoclonal
- Extra Details:
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituents of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are heterotrimers composed of 3 non-identical chains that adopt a cruciform structure with 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene and in some cases undergoes alternative splicing to give rise to separate chain variants. References: 1) Hirako Y., Yoshino K., Zillikens D., Owaribe K. Extracellular cleavage of bullous pemphigoid antigen 180/type XVII collagen and its involvement in hemidesmosomal disassembly. J Biochem. 2003 Feb;133(2):197-206. PMID: 12761182 2) Uematsu J., Nishizawa Y., Hirako Y., Kitamura K., Usukura J., Miyata T., Owaribe K. Both type-I hemidesmosomes and adherens-type junctions contribute to the cell-substratum adhesion system in myoepithelial cells. Eur J Cell Biol. 2005 Mar;84(2-3):407-15. PMID: 15819417 3) Owaribe K, Nishizawa Y, Franke WW. Isolation and characterization of hemidesmosomes from bovine corneal epithelial cells. Exp Cell Res. 1991 Feb;192(2):622-30. PMID:1988297, CAC
- Host:
- Mouse
- Immunogen:
- Laminin Alpha-4
- Reactivities:
- Human
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Monoclonal Antibody
