Anti Fish T-Cell Surface Glycoprotein CD4 monoclonal antibody (Clone 6D1)
Product Sizes
50 ul
CAC-NIH-NA-01-50UL
About this Product
- SKU:
- CAC-NIH-NA-01
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- Clone 6d1
- Clonality:
- Monoclonal
- Extra Details:
- The two major subsets of T lymphocytes, helper and cytotoxic T cells, are defined by expression of CD4 and CD8 glycoproteins, respectively. T cells expressing the CD4 surface antigen facilitate B-cell maturation and production of antibodies by B-cells and are thus termed "helper" T cells. CD4+ helper T cells recognize exogenously derived peptides in the context of MHC class II molecule expressed on antigen presenting cells. One (D1) of four Ig-like extracellular domains of CD4 primarily interacts with the A Alpha2 and B Beta2 domains of the MHC class II heterodimer. This antibody, raised against antigens from Ginbuna carp, permits flow cytometric and immunofluorescence analysis of CD4 helper T cells from zebrafish, goldfish and the cyprinid fish carp. Source: Dr. Teruyuki Nakanishi, Department of Veterinary Medicine, Faculty of Materials Science and Technology, University of Japan References: 1) Toda H., et al. Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish. Dev Comp Immunol. (2011) 35 (6), 650-660. 2) Shibasaki Y., et al. Kinetics of CD4 + and CD8A Alpha + T-cell subsets in Graft-Versus-Host Reaction (GVHR) in Gimbuna crucian carp Carassius auratus langsdorfii., CAC
- Host:
- Rat
- Immunogen:
- Fish T-Cell Surface Glycoprotein CD4
- Reactivities:
- Fish
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Monoclonal Antibody