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Antibodies

Anti DNA-Directed RNA Polymerase II Subunit RPB1 (POLR2A) CTD Phosopho-Ser5 monoclonal antibody (Clone 1H4B6)

Product Sizes
100 ug
£890.00
CAC-CEC-016-100UG
About this Product
SKU:
CAC-CEC-016
Application:
ChIP, ELISA, Immunocytochemistry, Western Blot
translate.label.attr.clone:
Clone 1h4b6
Clonality:
Monoclonal
Extra Details:
Background RNA polymerase II (RNAPII) transcribes all protein-coding genes and many non-coding genes, and the activity of RNAPII correlates with the phosphorylation state of RPB1, the large catalytic subunit of RNAPII.. RPB1 has an unusual C-terminal domain (CTD) that consists of repeats of the heptapeptide consensus sequence N-Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7-C, of which there are 52 copies in mammals. The amino acids in these repeats are potential targets for modification, such as phosphorylation and glycosylation. References 1) Odawara et al. (2011) BMC Genomics. 12:516. PMID: 22011111., CAC
Host:
Rat
Immunogen:
DNA-Directed RNA Polymerase II Subunit RPB1 (POLR2A) CTD Phosopho-Ser5
Reactivities:
Hamster, Human, Mouse, Non-human Primate, Rat
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
Cosmo Bio Ltd
Type:
Antibody: Monoclonal Antibody