Anti Histone H3.1 (HIST1H3A) T11ph monoclonal antibody (Clone 6G12C5)
Product Sizes
100 ug
CAC-CEC-002-100UG
About this Product
- SKU:
- CAC-CEC-002
- Application:
- ELISA, Immunocytochemistry, Western Blot
- translate.label.attr.clone:
- Clone 6g12c5
- Clonality:
- Monoclonal
- Extra Details:
- Background Post-translation modifications of histones modulate the accessibility and transcriptional competence of specific chromatin regions within the eukaryotic genome. Phosphorylation of histone H3 Threonine 11 (H3-T11ph) occurs throughout the cell cycle and is Chk1 dependent. It has been reported that DNA damage rapidly reduces H3-T11 phosphorylation. Application Western blotting: 1/500 Immunocytochemistry: 1/500 Other applications have not been tested. Optimal dilutions/concentrations should be determined by the end user. The composition of Histone H3 peptides and the reactivity of Histone H3 T11ph antibody, 6G12C5. H3 1 ARTKQTARK S T GGKAPRKQC 19 H3 K9ac 1 ARTKQTARKac S T GGKAPRKQC 19 H3 S10ph 1 ARTKQTARK Sph T GGKAPRKQC 19 H3 T11ph 1 ARTKQTARK S TphGGKAPRKQC 19 H3 K9acT11ph 1 ARTKQTARKac S TphGGKAPRKQC 19 H3 S10phT11ph 1 ARTKQTARK Sph TphGGKAPRKQC 19 H3.1 T32ph 21 ATKAARKSAPA TphGGVKKPH 39 H3.3 T32ph 21 ATKAARKSAPS TphGGVKKPH 39 References Shimada M, et al. (2008) Cell. 132(2):221-32. PMID: 18243098., CAC
- Host:
- Rat
- Immunogen:
- Histone H3.1 (HIST1H3A) T11ph
- Reactivities:
- Hamster, Human, Mouse, Non-human Primate, Rat
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C
- Supplier:
- Cosmo Bio Ltd
- Type:
- Antibody: Monoclonal Antibody
