ZAP-70 iFluor488
Product Sizes
50 tests
£434.00
4203112-50TESTS
About this Product
- SKU:
- 4203112
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- C-D12
- Clonality:
- Monoclonal
- Conjugate:
- iFluor™ 488
- Extra Details:
- The clone C-D12, a mouse monoclonal antibody selectively binds with the 70kd tyrosine phosphoprotein known as ZAP-70 which is usually associated with the Z Zeta-chain CD3-receptor-associated protein tyrosine kinase (PTK). It is a member of the Syk family that is localized exclusively to the cytosol of T cells and natural killer (NK) cells and is required for their cellular activation. It is generally considered the T-lymphocyte counterpart of Syk, a B-cell receptor (BCR)-associated kinase that belongs to the same PTK family and plays a similar role in the antigen receptor signaling in the B-lineage cells. It facilitates the upregulation of Fas ligand in activation-induced T cell apoptosis. ZAP-70 expression plays an important role in the clinical diagnosis of various types of hematologic malignancies.
- Host:
- Mouse
- Purity:
- >95%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Caprico Biotechnologies
- Type:
- Antibody: Monoclonal Antibody
