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Antibodies

BCL-2 APC

Product Sizes
100 tests
£626.00
4131045-100TESTS
About this Product
SKU:
4131045
Application:
Flow Cytometry
Clone:
100
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
The clone 100, a mouse monoclonal antibody, recognizes a 239 amino acid ~25kDa human apoptosis regulator oncoprotein known as Bcl-2. It is an intracellular, integral membrane protein containing up to 4 Bcl-2 homology (BH) motifs which are found primarily in the nuclear envelope, endoplasmic reticulum and outer mitochondrial membrane. Bcl-2 is a conserved anti-apoptotic protein and plays important roles in the management of normal immunity. Nonrandom translocations with breakpoint at band q21 on chromosome 18 may cause bcl-2 gene deregulation and contribute to neoplastic transformation in human lymphomas.
Host:
Mouse
Purity:
>95%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
Caprico Biotechnologies
Type:
Antibody: Monoclonal Antibody