CD1a PerCP-Cyanine5.5
Product Sizes
50 tests
£476.00
4115062-50TESTS
About this Product
- SKU:
- 4115062
- Application:
- Flow Cytometry
- Clone:
- OKT6
- Clonality:
- Monoclonal
- Conjugate:
- PerCP-Cyanine 5.5
- Extra Details:
- The clone OKT6, a mouse monoclonal antibody selectively recognizes 49-kDa type I transmembrane glycoprotein non-covalently associated with B Beta2-microglobulin known as CD1a. The CD1a glycoprotein has structural similarities to MHC class I molecule and plays important role in antigen-presenting mechanism to T-cell receptors present on NK T-cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation NK T-cells, CD1a has been implicated in thymic T cell development. CD1a has been used as a marker for DCs in a range of human tumors and the density of CD1a DC has been associated with clinical outcome in patients with lung, colon, gastric, nasopharyngeal, laryngeal and tongue carcinomas.
- Host:
- Mouse
- Purity:
- >95%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Caprico Biotechnologies
- Type:
- Antibody: Monoclonal Antibody