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Antibodies

CD1a PerCP-Cyanine5.5

Product Sizes
25 tests
£263.00
111564-25TESTS
About this Product
SKU:
111564
Application:
Flow Cytometry
Clone:
OKT6
Clonality:
Monoclonal
Conjugate:
PerCP-Cyanine 5.5
Extra Details:
The clone OKT6, a mouse monoclonal antibody selectively recognizes 49-kDa type I transmembrane glycoprotein non-covalently associated with B Beta2-microglobulin known as CD1a. The CD1a glycoprotein has structural similarities to MHC class I molecule and plays important role in antigen-presenting mechanism to T-cell receptors present on NK T-cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation NK T-cells, CD1a has been implicated in thymic T cell development. CD1a has been used as a marker for DCs in a range of human tumors and the density of CD1a DC has been associated with clinical outcome in patients with lung, colon, gastric, nasopharyngeal, laryngeal and tongue carcinomas.
Host:
Mouse
Purity:
>95%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
Caprico Biotechnologies
Type:
Antibody: Monoclonal Antibody