CD86 APC
Product Sizes
200 tests
£551.00
105746-200TESTS
About this Product
- SKU:
- 105746
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- BU63
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- BU63 recognizes ~70Kda a surface antigen protein of Ig superfamily characterized as CD86 expressed by most antigen presenting cells (APC). Depending on the immunological condition, CD86 specifically binds with its two ligands CD28 and CD152 (CTLA-4) expressed by T cells. Binding with CD28, CD86 provides stimulatory signal and activates T cells whereas binding with CD152 (CTLA-4) CD86 provides inhibitory signal to T cells. Generally, high-level CD86 expression was noticed on peripheral monocytes, tissue macrophages and dendritic cells, and also on activated B cells. CD86 is useful in the clinical diagnosis of cancer cells including malignant Hodgkin's and non-hodgkin's diseases.
- Host:
- Mouse
- Purity:
- >95%
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Caprico Biotechnologies
- Type:
- Antibody: Monoclonal Antibody
