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Proteins and Peptides

Guinea pig Interferon Gamma (IFNg), Active Protein

Product Sizes
50 ug
£1076.00
RPU54854-50UG
100 ug
£1313.00
RPU54854-100UG
1 mg
£5475.00
RPU54854-1MG
About this Product
SKU:
RPU54854
Additional Names:
IFG|IFI|IFN-G|IFN, Immune Interferon|INFr
Application:
Detection/Quantitation, Tissue Culture
Buffer:
Freeze-dried powder|PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
CE/IVD:
RUO
Extra Details:
Guinea pig Interferon Gamma (IFNg), Active Protein is a purified Prokaryotic Protein.
Formulation:
Freeze-dried powder
Immunogen:
Interferon Gamma (IFNg)
Molecular Weight:
18kDa
Physical State:
freeze-dried
Purity:
>90%
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Biomatik
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Catalog Protein.JPG
Interferon gamma (IFNG Gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The importance of IFNG Gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. It has been reported that IFN-G Gamma promotes production of inducible Nitric Oxide Synthase (iNOS) in macrophages as an important activator. After stimulated with IFN-G Gamma, morphological changes will occur in murine macrophage cell line (Raw 264.7 cells), and inducible nitric-oxide synthase (iNOS) in the cells will increase. Raw 264.7 cells were incubated in DMEM with IFN-G Gamma (10ng/mL) for 24h, then cells were observed by inverted microscope and iNOS in cell lysates was detected by ELISA. Effect of IFN-G Gamma on morphological change of Raw 246.7 cells was shown in Figure 1.
Effect of IFN-G Gamma on the expression of iNOS was shown in Table 1.