IL-13 (pig) ELISA kit
Product Sizes
96 wells
£912.00
A05422-96WELLS
About this Product
- SKU:
- A05422
- Additional Names:
- ELISA|EIA|Chemokine|IL-4|T helper cell subsets CD8+ T|mast cells|eosinophils|basophils|mononuclear phagocytic cells|endothelial cells|epithelial cells|B cells|inflammationallergic asthma|hyperresponsiveness
- Extra Details:
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins; hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time; scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Interleukin 13 (IL-13) is a nonglycosylated cytokine of 132 amino acids with a molecular weight of 12kDa and structured with four alpha-helices(1). IL-13 is secreted by T helper cell subsets; CD8+ T cells; mast cells; eosinophils and basophils(3). |It has 25 % of sequence homology with IL-4(1); they share their actions on mononuclear phagocytic cells; endothelial cells; epithelial cells; and B cells(4). Both are key factors in the development of allergic hypersensitivity; and they also play a major role in exacerbating allergic and asthmatic symptoms.|IL-13 is more importantly implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues(2). IL-13 is the central mediator of allergic asthma; where it regulates eosinophilic inflammation; mucus secretion; and airway hyperresponsiveness(4). It's could play role in the resistance of some intracellular parasitis by down regulated of pro-inflammatory cytokines.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- +4[o]C
- Supplier:
- Bertin Technologies
- Type:
- Assay Kits: ELISAs
