Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Assay Kits & ELISAs

IL-8 (pig) ELISA kit

Product Sizes
96 wells
£912.00
A05421-96WELLS
About this Product
SKU:
A05421
Additional Names:
ELISA|EIA|Chemokine|CXCR1|CXCR2|angiogenic|inflammation|Interleukin-8|chemotactic|monocytes|lymphocytes|basophils|eosinophils|PF4|CXCL8|GCP-1|GCP1|LECT|LUCT|LYNAP|MDNCF|MONAP|NAF|NAP-1|NAP1|T cell chemotactic factor|beta-thromboglobulin-like protein|chemokine (C-X-C motif) ligand 8|chemoctakin|granulocyte chemotactic
Extra Details:
Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins; hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time; scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|IL-8 is a polypeptide of 72-77 amino acids(1); known also as CXCL8; GCP-1 and NAP-1. Member of the CXC chemokine family; it can adopt a monomeric or homodimeric conformation containing a triple-stranded anti-parallel beta-sheet arranged in a Greek key and a long C-terminal helix(2). IL-8 could also form a heterodimer with PF4 activity(3). The receptors of IL-8 are CXCR1 and CXCR2(4).|IL-8 is mainly produced by macrophages(5). It acts as an angiogenic factor in human microvascular endothelial cells(6). The main role of IL-8 in inflammation is the recruitment of neutrophils(7); although it is also responsible for the chemotactic migration and activation of monocytes; lymphocytes; basophils; and eosinophils at sites of inflammation(8).
Shipping Conditions:
Blue Ice
Storage Conditions:
+4[o]C
Supplier:
Bertin Technologies
Type:
Assay Kits: ELISAs