IL-10 (pig) ELISA kit
Product Sizes
96 wells
£761.00
A05414-96WELLS
About this Product
- SKU:
- A05414
- Additional Names:
- ELISA|EIA|Cytokine|Tumor Necrosis Factor-alpha|Interleukin-6|Interleukin-1|IL-1 beta|Immunooncology
- Extra Details:
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins; hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time; scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Also known as cytokine synthesis inhibitory factor (CSIF); IL-10 is a polypeptide of 157 amino acids glycosylated. The mature IL-10 is an homodimer linked by two intrachain disulfi de bridges (each sub-unit is 157 aa).|IL-10 is produced by innate and non-innate cells; it is a cytokine of the innate and adaptive immunity.|The mammalian cells known to secrete IL-10 are NK cells; cytotoxic T cells; memory Th1 and Th2 cells; macrophages monocytes; B cells; dendritic cells; hepatic stellates; keratinocytes; fetal erythroblasts.|IL-10 is a cytokine with multiple pleiotropic effects in immunoregulation and infl ammation. IL-10 is characterized like anti-infl ammatory cytokine: it represses the expression of inflammatory cytokines; such as Tumor Necrosis Factor-alpha (TNF-alpha); Interleukin-6 (IL-6) and Interleukin-1 (IL-1 beta); in macrophage. IL-10 is an immunoregulation cytokine and negative regulate Th1 responses by downmodulating antigen presenting capacity of APC.|Due its central function; a dysregulation of the production of the lL-10 is implicated in asthma or autoimmune diseases.|IL-10 is currently studied in immunooncology.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- +4[o]C
- Supplier:
- Bertin Technologies
- Type:
- Assay Kits: ELISAs
