IFN-gamma 1 (pig) ELISA kit
Product Sizes
96 wells
£761.00
A05413-96WELLS
About this Product
- SKU:
- A05413
- Additional Names:
- ELISA|EIA|Cytokine|Antiviral|Immunoregulatory|Anti-tumor
- Extra Details:
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins; hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time; scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Also known as type II interferons; IFN-gamma is a glycoprotein of 146 amino acids.|IFN-gamma is a cytokine critical for the innate and adaptive immunity. It is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response and by T helper cells and cytotoxic T lymphocyte (CTL) as part of the adaptive immunity.|IFN-gamma has antiviral; immunoregulatory; and anti-tumor properties.|IFN-gamma:|> promotes the NK cell activity;|> increases the antigen presentation by action on the lysosome activity of macrophages;|> promotes Th1 differentiation; and suppresses Th2 differentiation which would cause a humoral (antibody) response;|> modulates the production of IgG2a and IgG3 from activated plasma B cells;|> increases expression of class I MHC molecules as well as class II MHC on antigen-presenting cells;|> promotes adhesion and binding required for leukocyte migration.|IFN-gamma interacts with other cytokines; either in a synergistic (e.g.; TNF) or antagonistic (e.g.; IL-4) fashion.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- +4[o]C
- Supplier:
- Bertin Technologies
- Type:
- Assay Kits: ELISAs
