Acylated Ghrelin (pig) ELISA kit
Product Sizes
96 wells
£763.00
A05401-96WELLS
About this Product
- SKU:
- A05401
- Additional Names:
- ELISA|spi-bio|acylated|immunoassays|obesity|growth|hormones|homeostasis|ligands|secretagogue|A05106|receptors|stomach|hypothalmic|spi-bio|spibio|adipokines|octanoyl|des-octanoyl|des octanoyl|pig|porcine|diabesity
- Extra Details:
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins; hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time; scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Bertin Bioreagent’s expertise is to develop analytical tools for biomarkers. As such; in 2004; Bertin Bioreagent launched its first Ghrelin Biomarker assay kits; under the SPI-Bio brand name; as a result of its state-of-the-art R&D research teams. Bertin Bioreagent was the first company providing bioanalytical tools to assay Acylated and Non-acylated Ghrelin with very high sensitivity.|Ghrelin discovered in 1999; is fast becoming an endocrinology target of the millennium. Ghrelin; identified in rat stomach as an endogenous ligand for the GH secretagogue receptor; is mainly produced in stomach; but has been demonstrated in many other organs. In addition to GH-releasing properties and its orexant action; ghrelin could act as an hormone having effects on gastric motility (similarity with the peptide hormone motilin); acidic secretion; cardiovascular action; antiproliferative effects; pancreatic and glucose metabolism function; sleep... Ghrelin gene raises to mRNA prepro-ghrelin of 117 amino acids. This precursor is processed into ghrelin; 28 amino acids (human). Before being secreted; this peptide is octanoylated at Ser 3. This step is essential for biological activity. If the endogenous peptide appears directly related to feeding behaviour; the potential therapeutic importance of this hormone is not restricted to a regulator of food intake but also may be involved osteoporosis somatopaus; infertility and ovulation induction; and some cardiovascular diseases.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Bertin Technologies
- Type:
- Assay Kits: ELISAs
