FABP4 (human) ELISA kit
Product Sizes
96 wells
£1033.00
A05181-96WELLS
About this Product
- SKU:
- A05181
- Additional Names:
- spi-bio|spibio|ELISA|immunoassay|enzyme|A05181|FABP4|fatty|acid|binding|protein|adipocytes|aP2|AFABP|diabesity
- Extra Details:
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins; hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time; scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Adipocyte Fatty Acid Binding Protein (AFABP) is a 15 kDa member of the intracellular Fatty Acid Binding Protein (FABP) family; which is known for the ability to bind fatty acids and related compounds.|AFABP is expressed in a tissue specific-manner in differentiated adipocytes and is a critical gene in the regulation of the biological function of these cells. According to some results; AFABP may be involved in mediating obesity-induced alterations in adipocyte gene expression. In macrophages AFABP modulates inflammatory responses and cholesterol ester accumulation; and total or macrophage-specific AFABP deficiency confers dramatic protection against atherosclerosis in the apoE-/- mice. These results indicate a central role for AFABP in the development of major components of the metabolic syndrome through its distinct actions in adipocytes and macrophages. Besides being active within the cell; AFAB appears to be a secreted protein; with unknown functions.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- +4[o]C
- Supplier:
- Bertin Technologies
- Type:
- Assay Kits: ELISAs
