Rat CD25 ELISA Kit
Product Sizes
96 wells
£733.00
ARG83662-96WELLS
About this Product
- SKU:
- ARG83662
- Additional Names:
- IL2RA; Interleukin 2 Receptor Subunit Alpha; CD25; Interleukin-2 Receptor Subunit Alpha; Interleukin 2 Receptor, Alpha; IL-2 Receptor Subunit Alpha; IL-2R Subunit Alpha; TAC Antigen; IDDM10; IL2R; P55; Insulin-Dependent Diabetes Mellitus 10; CD25 Antigen; IL-2-RA; IL2-RA; IMD41; TCGFR
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020]
- Immunogen:
- CD25
- Physical State:
- Cell Culture Supernatant, Plasma, Serum
- Reactivities:
- Rat
- Sensitivity:
- 50 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C, -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:ARG83662.html
