Caspase 3 Assay Kit
Product Sizes
96 wells
ARG83407-96WELLS
About this Product
- SKU:
- ARG83407
- Additional Names:
- CPP-32; Caspase-3; EC 3.4.22.56; Apopain; CASP-3; CPP32; Cysteine protease CPP32; SCA-1; SREBP cleavage activity 1; CPP32B; Protein Yama
- Application:
- Cell-based/Functional Assay
- CE/IVD:
- RUO
- Extra Details:
- Caspase-3 is a caspase protein that interacts with caspase-8 and caspase-9. It is encoded by the CASP3 gene. CASP3 orthologs have been identified in numerous mammals for which complete genome data are available. Unique orthologs are also present in birds, lizards, lissamphibians, and teleosts. The CASP3 protein is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6 and 7; and the protein itself is processed and activated by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein
- Immunogen:
- Caspase 3
- Physical State:
- Cell Lysate, Other Biological Fluid, Tissue Extract
- Reactivities:
- Other Species
- Sensitivity:
- 3 umol/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C, -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: Cell Viability
- Manufacturer's Data Sheet:ARG83407.html
