Human Factor VII ELISA Kit
Product Sizes
96 wells
£754.00
ARG83281-96WELLS
About this Product
- SKU:
- ARG83281
- Additional Names:
- Eptacog alfa; Coagulation factor VII; SPCA; Serum prothrombin conversion accelerator; EC 3.4.21.21; Proconvertin
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
- Immunogen:
- Factor VII
- Physical State:
- Cell Culture Supernatant, Plasma, Serum
- Range:
- 0.78 ng/ml - 50 ng/ml
- Reactivities:
- Human
- Sensitivity:
- 25 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:ARG83281.html
