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Assay Kits & ELISAs

Human CD46 ELISA Kit

Product Sizes
96 wells
£754.00
ARG83278-96WELLS
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG83278
Additional Names:
MIC10; TLX; CD antigen CD46; Trophoblast leukocyte common antigen; AHUS2; TRA2.10; Membrane cofactor protein; MCP
Application:
ELISA
CE/IVD:
RUO
Conjugate:
HRP
Extra Details:
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Immunogen:
CD46
Physical State:
Cell Culture Supernatant, Plasma, Serum
Range:
312 pg/ml - 20,000 pg/ml
Reactivities:
Human
Sensitivity:
25 pg/ml
Shipping Conditions:
Blue Ice
Specificity:
There is no detectable cross-reactivity with other relevant proteins.
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Assay Kits: ELISAs