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Assay Kits & ELISAs

Human Cathepsin C ELISA Kit

Product Sizes
96 wells
£754.00
ARG83261-96WELLS
Academic Pricing
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About this Product
SKU:
ARG83261
Additional Names:
CTSC; Cathepsin C; Dipeptidyl Peptidase 1; DPP1; Dipeptidyl Transferase; Cathepsin J; EC 3.4.14.1; DPP-I; CPPI; DPPI; PALS; PLS; Dipeptidyl-Peptidase I; Dipeptidyl Peptidase I; PDON1; HMS; JPD; JP
Application:
ELISA
CE/IVD:
RUO
Conjugate:
HRP
Extra Details:
This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
Immunogen:
Cathepsin C
Physical State:
Cell Culture Supernatant, Plasma, Serum
Range:
156 pg/ml - 10,000 pg/ml
Reactivities:
Human
Sensitivity:
100 pg/ml
Shipping Conditions:
Blue Ice
Specificity:
There is no detectable cross-reactivity with other relevant proteins.
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Assay Kits: ELISAs