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Assay Kits & ELISAs

Human CASPR2 ELISA Kit

Product Sizes
96 wells
£754.00
ARG83254-96WELLS
Academic Pricing
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About this Product
SKU:
ARG83254
Additional Names:
CNTNAP2; Contactin Associated Protein 2; KIAA0868; NRXN4; Contactin Associated Protein Like 2; Contactin-Associated Protein-Like 2; Cell Recognition Molecule Caspr2; Caspr2; CASPR2; Homolog Of Drosophila Neurexin IV; AUTS15; PTHSL1; CDFE
Application:
ELISA
CE/IVD:
RUO
Conjugate:
HRP
Extra Details:
This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability.
Immunogen:
CASPR2
Physical State:
Cell Culture Supernatant, Plasma, Serum
Range:
15.6 pg/ml - 1,000 pg/ml
Reactivities:
Human
Sensitivity:
13 pg/ml
Shipping Conditions:
Blue Ice
Specificity:
There is no detectable cross-reactivity with other relevant proteins.
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Assay Kits: ELISAs