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Assay Kits & ELISAs

Human Complement C2 ELISA Kit

Product Sizes
96 wells
£754.00
ARG83228-96WELLS
Academic Pricing
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About this Product
SKU:
ARG83228
Additional Names:
C2; Complement C2; Complement Component 2; C3/C5 Convertase; EC 3.4.21.43; Complement Component C2; EC 3.4.21; ARMD14; CO2
Application:
ELISA
CE/IVD:
RUO
Conjugate:
HRP
Extra Details:
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Immunogen:
Complement C2
Physical State:
Cell Culture Supernatant, Plasma, Serum, Urine
Range:
312 pg/ml - 20,000 pg/ml
Reactivities:
Human
Sensitivity:
25 pg/ml
Shipping Conditions:
Blue Ice
Specificity:
There is no detectable cross-reactivity with other relevant proteins.
Storage Conditions:
2-8[o]C
Supplier:
Arigo Biolaboratories
Type:
Assay Kits: ELISAs