Human ACY1 / Aminoacylase 1 ELISA Kit
Product Sizes
96 wells
£754.00
ARG83225-96WELLS
About this Product
- SKU:
- ARG83225
- Additional Names:
- ACY-1; N-acyl-L-amino-acid amidohydrolase; ACY1D; EC 3.5.1.14; HEL-S-5; Aminoacylase-1
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Nov 2010]
- Immunogen:
- ACY1 / Aminoacylase 1
- Physical State:
- Cell Culture Supernatant, Plasma, Serum
- Range:
- 312 pg/ml - 20,000 pg/ml
- Reactivities:
- Human
- Sensitivity:
- 25 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:ARG83225.html
