Human GDNF ELISA Kit
Product Sizes
96 wells
£550.00
ARG83038-96WELLS
About this Product
- SKU:
- ARG83038
- Additional Names:
- GDNF, Glial Cell Derived Neurotrophic Factor, Astrocyte-Derived Trophic Factor, HFB1 GDNF, ATF1, ATF2, Glial Cell Line Derived Neurotrophic Factor, ATF, Glial Cell Line Derived Neurotrophic Factor, Glial Derived Neurotrophic Factor, HSCR, HGDNF
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
- Immunogen:
- GDNF
- Physical State:
- Ascites, Cell Culture Supernatant, Plasma, Serum, Urine
- Reactivities:
- Human
- Sensitivity:
- 0.14 ng/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Cross-reacts with: Mouse GDNF (50%).Rat GDNF (50%).Not cross-reacts with:Human BDNF, CNTF, beta NGF, Syndecan 3, Neurturin.Mouse BDNF, CNTF, beta NGF, Neurturin.Rat BDNF, CNTF, beta NGF, Neurturin.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:ARG83038.html
