Human CD135 / FLT3 ELISA Kit
Product Sizes
96 wells
£776.00
ARG82733-96WELLS
About this Product
- SKU:
- ARG82733
- Additional Names:
- CD135; FLK2; Receptor-type tyrosine-protein kinase FLT3; FLK-2; STK-1; STK1; FL cytokine receptor; FLT-3; Stem cell tyrosine kinase 1; Fetal liver kinase-2; Fms-like tyrosine kinase 3; CD antigen CD135; EC 2.7.10.1
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
- Immunogen:
- CD135 / FLT3
- Physical State:
- Cell Culture Supernatant, Plasma, Serum
- Reactivities:
- Human
- Sensitivity:
- 50 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:ARG82733.html
