Human MMP14 / MT1-MMP Assay Kit
Product Sizes
96 wells
£1117.00
ARG82633-96WELLS
About this Product
- SKU:
- ARG82633
- Additional Names:
- MT1MMP; MT-MMP 1; Membrane-type matrix metalloproteinase 1; MT1-MMP; Membrane-type-1 matrix metalloproteinase; MT-MMP; EC 3.4.24.80; MMP-X1; MMP-14; Matrix metalloproteinase-14; WNCHRS; MTMMP1
- Application:
- Cell-based/Functional Assay
- CE/IVD:
- RUO
- Extra Details:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
- Immunogen:
- MMP14 / MT1-MMP
- Physical State:
- Cell Lysate, Tissue Lysate
- Reactivities:
- Human
- Sensitivity:
- 500 pg/ml for 2 hours incubation100 pg/ml for 5 hours incubation
- Shipping Conditions:
- Blue Ice
- Specificity:
- Measures endogenous active MMP14 (naturally occurring).
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: Detection
- Manufacturer's Data Sheet:ARG82633.html
