Human CD124 / IL4 Receptor ELISA Kit
Product Sizes
96 wells
£776.00
ARG81315-96WELLS
About this Product
- SKU:
- ARG81315
- Additional Names:
- CD124; IL-4RA; IL-4R subunit alpha; Soluble IL-4R-alpha; IL-4 receptor subunit alpha; IL4RA; CD antigen CD124; sIL4Ralpha/prot; Soluble IL-4 receptor subunit alpha; IL-4R-alpha; IL-4-binding protein; IL4-BP; Interleukin-4 receptor subunit alpha
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
- Immunogen:
- CD124 / IL4 Receptor
- Physical State:
- Cell Culture Supernatant, Plasma, Serum
- Reactivities:
- Human
- Sensitivity:
- 11.5 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Recognizes both natural and recombinant Human soluble IL4 Receptor. No cross reactivity with other Human soluble receptors.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:ARG81315.html
