Human IL29 / IFN lambda ELISA Kit
Product Sizes
96 wells
£490.00
ARG80169-96WELLS
About this Product
- SKU:
- ARG80169
- Additional Names:
- IFN-lambda-1; IL-29; Interferon lambda-1; Interleukin-29; Cytokine Zcyto21; IL29
- Application:
- ELISA
- CE/IVD:
- RUO
- Conjugate:
- HRP
- Extra Details:
- IL-29 is distantly related to type I interferons and the IL-10 family. Expression of IL-29 is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor beta (IL10RB) and interleukin 28 receptor alpha . IL-29 exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumour activity. IL-29 acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-29 produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. IFN-Lambda 1 antiviral and antiproliferative activity requires Interferon-Lambda 2 receptor tyrosine residues. Recombinant human IL-29 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 181 amino acids and having a molecular mass of?20 kDa.
- Immunogen:
- IL29 / IFN lambda
- Physical State:
- Cell Culture Supernatant, Plasma, Serum
- Reactivities:
- Human
- Sensitivity:
- 4 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- No significant cross-reactivity or interference with Human IFN-A AlphaA/D, IFN-A AlphaA, IFN-A AlphaB2, IFN-A AlphaG, IFN-A AlphaI, IFN-B Beta1a, IL-10 RB BetaFc Chimera
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:ARG80169.html
