anti-Claudin 18.2 antibody [SQab22278]
Product Sizes
20 ul
£221.00
ARG67014-20UL
100 ul
£477.00
ARG67014-100UL
About this Product
- SKU:
- ARG67014
- Additional Names:
- Isoform 2 of Claudin-18; Claudin-18 isoform 2; Claudin-18.2; Anti-Claudin 18.2 Antibody; SQab22278; Arigo Biolaboratories; Western blot; immunoprecipitation; immunofluorescence; tight junctions; epithelial cells; protein expression; tissue and cell studies; research use
- Application:
- IHC-Paraffin
- Buffer:
- PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
- CE/IVD:
- RUO
- translate.label.attr.clone:
- SQab22278
- Clonality:
- Monoclonal
- Extra Details:
- Claudin18.2 (CLDN18.2) is a splice variant of the membrane epithelial tight junctions protein Claudin18 (CLDN18) and has been identified as a promising biomarker for targeted therapy. While upon malignant transformation, the changes in cell polarity lead to the exposure of CLDN18.2 epitopes. which are suitable for targeted therapy. Prior evidence demonstrates that except for GC, CLDN18.2 is aberrantly expressed in various primary tumors and metastases, including pancreatic, biliary, ovarian, and lung adenocarcinomas, which makes CLDN18.2 a pan-cancer target. CLDN18.2 has a restricted expression profile in normal tissues, it physiologically expresses only in the tight junction supramolecular complex of gastric mucosa.
- Host:
- Rabbit
- Immunogen:
- Recombinant Protein of Human Claudin 18.2.
- Isotype:
- IgG
- Purification:
- Protein A Purified; Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG67014.html
