anti-CD45R0 antibody [UCHL1]
Product Sizes
100 ug
£488.00
ARG65549-100UG
About this Product
- SKU:
- ARG65549
- Additional Names:
- LY5; GP180; Receptor-type tyrosine-protein phosphatase C; CD45; L-CA; CD antigen CD45; Leukocyte common antigen; CD45R; LCA; T200; EC 3.1.3.48; B220
- Application:
- Flow Cytometry, IHC-Frozen, IHC-Paraffin, Immunoprecipitation, Mass Cytometry
- Buffer:
- PBS (pH 7.4) and 15 mM Sodium azide
- CE/IVD:
- RUO
- translate.label.attr.clone:
- UCHL1
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
- Host:
- Mouse
- Immunogen:
- Human IL-2 dependent T cells
- Isotype:
- IgG2a
- Purity:
- >95%
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The clone UCHL1 recognizes CD45R0, a 180 kDa low molecular weight isoform of the leukocyte common antigen (LCA). The antigen is expressed on a subset of memory/activated T cells and on cortical thymocytes.HLDA III; WS Code NL 826HLDA III; WS Code T 128HLDA IV; WS Code NL 31HLDA V; WS Code BP BP460HLDA V; WS Code T T-081HLDA V; WS Code T T-CD45.43
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG65549.html
