anti-CD86 antibody [BU63]
Product Sizes
100 ug
£477.00
ARG65423-100UG
About this Product
- SKU:
- ARG65423
- Additional Names:
- B70; B7.2; LAB72; CD antigen CD86; B7-2; FUN-1; CD28LG2; T-lymphocyte activation antigen CD86; CTLA-4 counter-receptor B7.2; Activation B7-2 antigen; BU63
- Application:
- Cell-based/Functional Assay, Flow Cytometry, IHC-Frozen, Immunoprecipitation, Western Blot
- Buffer:
- PBS (pH 7.4) and 15 mM Sodium azide
- CE/IVD:
- RUO
- translate.label.attr.clone:
- BU63
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
- Host:
- Mouse
- Immunogen:
- B-lymphoblastoid cell line ARH 77
- Isotype:
- IgG1
- Purity:
- >95%
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The clone BU63 reacts with CD86 (B7-2), a 70 kDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes. HLDA V; WS Code BP BP072 HLDA V; WS Code A A109 HLDA VI; WS Code BP 95 HLDA VI; WS Code B CD86.9
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:ARG65423.html
