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Antibodies

anti-CD258 / LIGHT antibody

Product Sizes
100 ug
£616.00
ARG65034-100UG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
ARG65034
Additional Names:
CD258; Herpes virus entry mediator ligand; HVEML; HVEM-L; Herpesvirus entry mediator ligand; LTg; LIGHT; CD antigen CD258; TR2; Tumor necrosis factor ligand superfamily member 14
Application:
Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Host:
Goat
Immunogen:
C-HEVNPAAHLTGANS
Isotype:
IgG
Purification:
Purified from goat serum by antigen affinity chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is expected to recognize both reported isoforms (NP_003798.2; NP_742011.1).
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Antibody: Polyclonal Antibody