anti-SPHK1 antibody
Product Sizes
100 ug
£616.00
ARG64693-100UG
About this Product
- SKU:
- ARG64693
- Additional Names:
- SK 1; SPK 1; EC 2.7.1.91; SPHK; Sphingosine kinase 1
- Application:
- Immunoprecipitation, Western Blot
- Buffer:
- Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Host:
- Goat
- Immunogen:
- C-DVDLESEKYRRLGE
- Isotype:
- IgG
- Purification:
- Purified from goat serum by antigen affinity chromatography.
- Reactivities:
- Bovine, Canine, Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is expected to recognise all three reported isoforms (NP_068807.2; NP_892010.2; NP_001136073.1). Reported variants represent identical protein (NP_001136073.1; NP_001136074.1).
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARG64693.html
